Professor Michael Dine is a leading high-energy theorist, who did ground-breaking work on supersymmetry, cosmology, and string theory. He has played a key role in the exploration of possible robust implications of string theory for physics at low energies. In his lecture series, Dine outlined the prospects and challenges facing the field as experiments at the CERN Large Hadron Collider draw near, and gave a critical introduction to the "Landscape" of string theory vacua, focusing on its predictivity and testability in collider experiments and cosmology.